Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237668 | 0.91 | HRH3 (0.44) | HRH3NOS3NOS1NOS2MAOA | |
| SCHEMBL4233991 | 0.82 | HRH3 (0.56) | HRH3MAOAMAOBGPR6DRD2 | |
| SCHEMBL4236980 | 0.82 | HRH3 (0.56) | HRH3NOS3NOS1NOS2MAOA | |
| SCHEMBL4238943 | 0.78 | HTR4 (0.45) | MAOAMAOBHTR4ADRA2BADRA2C | |
| SCHEMBL4233686 | 0.77 | HRH1 (0.39) | GPR6DRD2HTR2CHRH1KCNH2 | |
| SCHEMBL4238793 | 0.75 | MAOA (0.43) | HRH3MAOAMAOBHTR4HTR2C | |
| SCHEMBL4689209 | 0.74 | GPR6 (0.40) | HRH3GPR6HRH1KCNH2CCR3 | |
| SCHEMBL4228461 | 0.74 | HRH3 (0.57) | HRH3MAOAMAOBDRD2DRD3 | |
| SCHEMBL4231975 | 0.74 | HRH3 (0.57) | HRH3NOS3NOS1NOS2MAOA | |
| SCHEMBL4232384 | 0.73 | HRH3 (0.56) | HRH3NOS3NOS1NOS2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | HRH3 210/4885NOS3 3656/4885NOS1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.