⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324807 | 0.79 | — | — | |
| SCHEMBL9110469 | 0.79 | — | — | |
| SCHEMBL11427303 | 0.79 | — | — | |
| SCHEMBL462094 | 0.76 | — | — | |
| SCHEMBL530949 | 0.75 | FDPS (0.35) | — | |
| SCHEMBL1985743 | 0.74 | — | — | |
| SCHEMBL247632 | 0.74 | — | — | |
| SCHEMBL8311218 | 0.74 | — | — | |
| SCHEMBL9095283 | 0.74 | — | — | |
| SCHEMBL8267525 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270447-A1 | 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof | WYETH (US) | 2009-10-29 | — | — | US | disclosed |
| WO-2009120849-A1 | 2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | WYETH (US) | 2009-10-01 | — | — | WO | disclosed |