Sugi Predict

Sugi Predict / Compounds / SCHEMBL530949

SCHEMBL530949

SCHEMBL530949

COC=CCc1nccs1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ PKM P14618 1/20 0.35
▸ CHRM2 P08172 2/20 0.34
▸ CHRM1 P11229 2/20 0.34
▸ CHRM3 P20309 2/20 0.34
▸ CYP3A4 P08684 3/20 0.33
▸ TSHR P16473 3/20 0.33
▸ CYP2D6 P10635 2/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ LTA4H P09960 1/20 0.33
▸ SLC6A3 Q01959 2/20 0.33
▸ MAPK1 P28482 1/20 0.32
▸ TRPM8 Q7Z2W7 1/20 0.31
▸ NOS1 P29475 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ FBP1 P09467 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL324807 0.75 — —
SCHEMBL9110469 0.75 — —
SCHEMBL11427303 0.75 — —
SCHEMBL4237987 0.75 — —
SCHEMBL1985743 0.74 — —
SCHEMBL462094 0.71 — —
SCHEMBL291398 0.70 MAPT (0.43) FDPSALDH1A1PKMCYP3A4TSHR
SCHEMBL247632 0.70 — —
SCHEMBL8311218 0.70 — —
SCHEMBL3109516 0.70 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064929-A1 Modulating body/cranial hair growth DURANTON ALBERT (FR) 2003-04-03 — — US claimed
EP-0648488-B1 Method to alter hairgrowth and compositions therefor OREAL (FR) 2000-11-29 — — EP claimed
US-5928654-A Modulating body/cranial hair growth with lipoxygenase/cyclooxygenase inhibitors SOCIETE L'OREAL S.A. (FR) 1999-07-27 — — US claimed
EP-0800815-A2 Use of at least one lypoxygenase inhibitor and at least one cyclo-oxygenase inhibitor to alter hair growth L'OREAL (FR) 1997-10-15 — — EP claimed
EP-0648488-A1 Method to alter hairgrowth and compositions therefor L'OREAL (FR) 1995-04-19 — — EP claimed
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 — — US disclosed
US-20240190981-A1 Humanized Anti-CD70 Binding Agents and Uses Thereof SEAGEN INC (US) 2024-06-13 — — US disclosed
US-20240182580-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2024-06-06 — — US disclosed
WO-2024091979-A1 CD276 (B7-H3) ANTIBODY-DRUG CONJUGATES BRICKBIO, INC. (US) 2024-05-02 — — WO disclosed
US-11958909-B2 Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use SUTRO BIOPHARMA, INC. (US) 2024-04-16 — — US disclosed
EP-3488870-B1 ANTI-CD70 ANTIBODY DRUG CONJUGATES AMBRX INC (US) 2024-03-20 — — EP disclosed
US-20240084031-A1 VARIANT TARGET BINDING AGENTS AND USES THEREOF SEAGEN INC. (US) 2024-03-14 — — US disclosed
EP-1229034-A1 Nicotinamide derivatives and their mimetics as inhibitors of PDE4 isozymes Pfizer Products Inc. (US) 2002-08-07 — — EP disclosed
WO-2002051814-A1 BENZOYLPYRIDAZINES MERCK PATENT GMBH (DE) 2002-07-04 — — WO disclosed
WO-2001057025-A1 PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES PFIZER PRODUCTS INC. (US) 2001-08-09 — — WO disclosed
WO-2001057036-A1 NICOTINAMIDE BENZOFUSED-HETEROCYCLYL DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE4 ISOZYMES PFIZER PRODUCTS INC. (US) 2001-08-09 — — WO disclosed
EP-0648488-B1 Method to alter hairgrowth and compositions therefor OREAL (FR) 2000-11-29 — — EP disclosed
US-5928654-A Modulating body/cranial hair growth with lipoxygenase/cyclooxygenase inhibitors SOCIETE L'OREAL S.A. (FR) 1999-07-27 — — US disclosed
EP-0800815-A2 Use of at least one lypoxygenase inhibitor and at least one cyclo-oxygenase inhibitor to alter hair growth L'OREAL (FR) 1997-10-15 — — EP disclosed
EP-0648488-A1 Method to alter hairgrowth and compositions therefor L'OREAL (FR) 1995-04-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037405-B2 Anti-CD70 antibody drug conjugates CD74, CD63, CD47 FDPS 3197/4885ALDH1A1 868/4885PKM 4837/4885
US-20240084031-A1 VARIANT TARGET BINDING AGENTS AND USES THEREOF CD74, CD2BP2, TSG101 FDPS 2849/4885ALDH1A1 3624/4885PKM 4755/4885
US-20240182580-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES CD74, CD63, CD99 FDPS 4852/4885ALDH1A1 1241/4885PKM 4766/4885
US-11958909-B2 Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use DNPEP, LNPEP, ANPEP FDPS 4144/4885ALDH1A1 4661/4885PKM 4505/4885
US-20030064929-A1 Modulating body/cranial hair growth ALOX15B, ALOX12, ALOX5 FDPS 1988/4885ALDH1A1 422/4885PKM 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.