SCHEMBL4238765

SCHEMBL4238765

CCC(CC)NC(=O)Nc1ccc(Oc2ccc(NC(=O)c3ccc(OC4CCN(C(C)C)CC4)cc3)cc2COC)cc1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 13/20 0.47
CSF1R P07333 1/20 0.42
FLT3 P36888 1/20 0.42
PKM P14618 1/20 0.41
SLC5A7 Q9GZV3 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4233481 1.00 HRH3 (0.47) HRH3CSF1RFLT3PKMSLC5A7
SCHEMBL4683501 0.96 HRH3 (0.43) HRH3CSF1RFLT3PKMSLC5A7
SCHEMBL4232082 0.93 HRH3 (0.45) HRH3CSF1RFLT3SLC5A7
SCHEMBL13699306 0.93 SLC5A7 (0.44) HRH3CSF1RFLT3PKMSLC5A7
SCHEMBL4743227 0.93 HRH3 (0.40) HRH3PKMSLC5A7POLB
SCHEMBL4683606 0.91 HRH3 (0.42) HRH3CSF1RFLT3PKMSLC5A7
SCHEMBL4236845 0.91 HRH3 (0.48) HRH3CSF1RFLT3PKMSLC5A7
SCHEMBL4234320 0.91 HRH3 (0.48) HRH3PKMSLC5A7POLB
SCHEMBL4233292 0.91 HRH3 (0.48) HRH3CSF1RFLT3PKMSLC5A7
SCHEMBL4237153 0.90 HRH3 (0.48) HRH3CSF1RFLT3PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233910-A1 Npy antagonists, preparation and uses NPY1R, NPY5R, NPY2R HRH3 210/4885CSF1R 1368/4885FLT3 662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.