Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233481 | 0.96 | HRH3 (0.47) | HRH3PKMSLC5A7POLBCSF1R | |
| SCHEMBL4238765 | 0.96 | HRH3 (0.47) | HRH3PKMSLC5A7POLBCSF1R | |
| SCHEMBL4743227 | 0.96 | HRH3 (0.40) | HRH3PKMMCHR1SLC5A7POLB | |
| SCHEMBL4233292 | 0.95 | HRH3 (0.48) | HRH3PKMMCHR1SLC5A7POLB | |
| SCHEMBL4236845 | 0.95 | HRH3 (0.48) | HRH3PKMMCHR1SLC5A7POLB | |
| SCHEMBL4234320 | 0.92 | HRH3 (0.48) | HRH3PKMSLC5A7POLBNPC1 | |
| SCHEMBL4231912 | 0.90 | PKM (0.45) | HRH3PKMMCHR1NPC1ALDH1A1 | |
| SCHEMBL4232082 | 0.90 | HRH3 (0.45) | HRH3SLC5A7CSF1RFLT3 | |
| SCHEMBL13699306 | 0.89 | SLC5A7 (0.44) | HRH3PKMSLC5A7CSF1RFLT3 | |
| SCHEMBL4235406 | 0.88 | HRH3 (0.46) | HRH3MCHR1SLC5A7NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |