SCHEMBL13699306

SCHEMBL13699306

CCC(CC)NC(=O)Nc1ccc(Oc2ccc(NC(=O)c3cccc(OC4CCN(C(C)C)CC4)c3)cc2)c(COC)c1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC5A7 Q9GZV3 2/20 0.44
AR P10275 2/20 0.41
PGR P06401 1/20 0.41
HRH3 Q9Y5N1 5/20 0.40
CSF1R P07333 1/20 0.40
FLT3 P36888 1/20 0.40
OPRK1 P41145 2/20 0.39
PKM P14618 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4233751 0.96 SLC5A7 (0.44) SLC5A7ARPGRHRH3OPRK1
SCHEMBL4238765 0.93 HRH3 (0.47) SLC5A7HRH3CSF1RFLT3PKM
SCHEMBL4233481 0.93 HRH3 (0.47) SLC5A7HRH3CSF1RFLT3PKM
SCHEMBL4232714 0.91 SLC5A7 (0.45) SLC5A7ARPGRHRH3PKM
SCHEMBL4683501 0.89 HRH3 (0.43) SLC5A7HRH3CSF1RFLT3PKM
SCHEMBL4238304 0.87 SLC5A7 (0.41) SLC5A7CSF1RFLT3CYP3A4CYP2D6
SCHEMBL4232082 0.86 HRH3 (0.45) SLC5A7HRH3CSF1RFLT3
SCHEMBL4236439 0.86 SLC5A7 (0.45) SLC5A7ARPGRHRH3OPRK1
SCHEMBL4743227 0.86 HRH3 (0.40) SLC5A7ARPGRHRH3PKM
SCHEMBL4683530 0.85 OPRK1 (0.37) ARPGROPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233910-A1 Npy antagonists, preparation and uses NPY1R, NPY5R, NPY2R SLC5A7 1426/4885AR 1029/4885PGR 336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.