Acetone

Acetone

SCHEMBL4238945

CC(C)=O.COC(OC)N(C)C

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11286573 0.92 FFAR3 (0.39) ALDH1A1
SCHEMBL978 0.84
Ammonia Solution, Strong SCHEMBL29020067 0.81
Hydrochloric Acid SCHEMBL30521236 0.81
Dimethylformamide SCHEMBL2184967 0.74 TSHR (0.50)
Acetone SCHEMBL28830100 0.67
SCHEMBL19391024 0.67
Acetone SCHEMBL11782633 0.65
Acetone SCHEMBL593191 0.65 LMNA (0.43) LMNAALDH1A1
Acetone SCHEMBL7573994 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561852-A Pyrimidopyrazoles oxazolines compound and preparation method and application thereof 贵州大学 2024-08-30 CN claimed
CN-118561852-A Pyrimidopyrazoles oxazolines compound and preparation method and application thereof 贵州大学 2024-08-30 CN disclosed
US-20090149458-A1 PYRROLO[3,2-d]PYRIMIDINE COMPOUNDS AND THEIR USE AS PI3 KINASE AND mTOR KINASE INHIBITORS WYETH (US) 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149458-A1 PYRROLO[3,2-d]PYRIMIDINE COMPOUNDS AND THEIR USE AS PI3 KINASE AND mTOR KINASE INHIBITORS MTOR, PIK3CA, PIK3CD LMNA 4677/4885ALDH1A1 3923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.