Acetone

Acetone

SCHEMBL593191

CC(C)=O.COC(C)OC

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
TP53 P04637 1/20 0.32
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL10711426 0.90 FFAR3 (0.47) LMNAALDH1A1TSHRSMN1; SMN2TDP1
Acetamide SCHEMBL11118916 0.87 LMNA (0.50) LMNAALDH1A1TSHRSMN1; SMN2TDP1
Bicarbonate SCHEMBL6258274 0.86 TP53 (0.39) ALDH1A1TSHRSMN1; SMN2SLC1A3SLC1A2
Methylglyoxal SCHEMBL950599 0.82 ALDH1A1 (0.33) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
Butanone SCHEMBL8748901 0.82 ALDH1A1 (0.56) LMNAALDH1A1TSHRTDP1MGAM
SCHEMBL349574 0.82 TSHR (0.33) ALDH1A1TSHR
Acetone SCHEMBL28830100 0.81
Methyl Alcohol SCHEMBL3869122 0.81
SCHEMBL11615697 0.80
SCHEMBL1153 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719978-B1 A process for distributing ultra high purity gases with minimized corrosion L AIR LIQUIDE SA POUR BR L ETU (FR) 2001-10-24 EP claimed
US-5676762-A Process for distributing ultra high purity gases with minimized corrosion L'AIR LIQUIDE (FR) 1997-10-14 US claimed
US-5665172-A Method for washing an article with composition having a brominated hydrocarbon and stabilizer DIPSOL CHEMICALS CO., LTD. (JP) 1997-09-09 US claimed
US-5591273-A Process for distributing ultra high purity gases with minimized contamination and particulates L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1997-01-07 US claimed
EP-0719979-A2 A process for distributing ultra high purity gases with minimized contamination and particules L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1996-07-03 EP claimed
EP-0719978-A2 A process for distributing ultra high purity gases with minimized corrosion L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1996-07-03 EP claimed
US-4328356-A Process for preparing esters of arylacetic acids from alpha-halo-alkylarylketones MONTEDISON S.P.A. (IT) 1982-05-04 US claimed
JP-5140777-A None JP disclosed
JP-8296800-A None JP disclosed
EP-3333155-B1 METHOD FOR PRODUCING PITAVASTATIN CALCIUM API CORP (JP) 2023-05-24 EP disclosed
US-20230041342-A1 ALKYLATED NUCLEOSIDES, AND COMPOSITIONS AND METHODS THEREOF FOR NUCLEIC ACID DELIVERY Microvascular Therapeutics LLC (US) 2023-02-09 US disclosed
EP-4087929-A1 ALKYLATED NUCLEOSIDES, AND COMPOSITIONS AND METHODS THEREOF FOR NUCLEIC ACID DELIVERY Microvascular Therapeutics LLC (US) 2022-11-16 EP disclosed
WO-2021142059-A1 ALKYLATED NUCLEOSIDES, AND COMPOSITIONS AND METHODS THEREOF FOR NUCLEIC ACID DELIVERY MICROVASCULAR THERAPEUTICS, LLC (US) 2021-07-15 WO disclosed
EP-0035046-B1 NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-10-02 EP disclosed
EP-0081993-A2 Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1983-06-22 EP disclosed
EP-0068709-A1 Herbicide antidotes, production, use and compositions thereof STAUFFER CHEMICAL COMPANY (US) 1983-01-05 EP disclosed
US-4328356-A Process for preparing esters of arylacetic acids from alpha-halo-alkylarylketones MONTEDISON S.P.A. (IT) 1982-05-04 US disclosed
EP-0035046-A1 Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-09 EP disclosed
US-4138492-A FOR TREATMENT OF GASTROINTESTINAL DISORDERS ANPHAR, S.A. (ES) 1979-02-06 US disclosed
US-4115641-A CARDIAC AND CIRCULATORY-DYNAMIC PROPERTIES, ANGINA PECTORIS HOFFMANN-LA ROCHE INC. (US) 1978-09-19 US disclosed