Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.65 |
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238950 | 1.00 | GAA (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL13693824 | 1.00 | GAA (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL21114872 | 0.83 | MAPT (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL21114874 | 0.83 | MAPT (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL21114857 | 0.83 | ALDH1A1 (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL21114859 | 0.83 | ALDH1A1 (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL13624627 | 0.82 | GAA (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL4904047 | 0.82 | GAA (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL4904052 | 0.82 | GAA (0.65) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL22529440 | 0.81 | MAPT (0.66) | GAAMAPTALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |