⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141927 | 0.76 | — | — | |
| SCHEMBL21821290 | 0.66 | SLC18A3 (0.33) | — | |
| SCHEMBL12318246 | 0.65 | LMNA (0.33) | — | |
| SCHEMBL12318242 | 0.65 | CA1 (0.37) | — | |
| SCHEMBL2402406 | 0.65 | ALDH1A1 (0.33) | — | |
| Bromide SCHEMBL17338082 | 0.65 | SLC18A3 (0.33) | — | |
| Bromide SCHEMBL2403004 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL16271551 | 0.63 | KDM4E (0.43) | — | |
| SCHEMBL7424166 | 0.61 | TTR (0.31) | — | |
| SCHEMBL16973866 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722864-B2 | Glycosylated acetaminophen pro-drug analogs | NuTek Pharma Ltd. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130217640-A1 | GLYCOSYLATED ACETAMINOPHEN PRO-DRUG | NuTek Pharma Ltd. | 2013-08-22 | — | — | US | disclosed |
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | NuTek Pharma Ltd. | 2012-01-26 | — | — | US | disclosed |
| WO-2012012339-A2 | GLYCOSYLATED ACETAMINOPHEN PRO-DRUG ANALOGS | NuTek Pharma Ltd. (US) | 2012-01-26 | — | — | WO | disclosed |