Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amfenac SCHEMBL10824627 | 0.98 | ABCB11 (0.74) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL10589034 | 0.98 | ABCB11 (0.74) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL24249 | 0.98 | ABCB11 (0.78) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL30777846 | 0.98 | ABCB11 (0.78) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL9998546 | 0.97 | ABCB11 (0.76) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL11726346 | 0.97 | ABCB11 (0.76) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL11168965 | 0.97 | ABCB11 (0.76) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL9747734 | 0.97 | ABCB11 (0.76) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL9747027 | 0.97 | ABCB11 (0.76) | ABCB11LMNAPTGS1ADORA1PTGS2 | |
| Amfenac SCHEMBL11467022 | 0.95 | ABCB11 (0.74) | ABCB11LMNAPTGS1ADORA1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3742 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212179-A2 | THERAPEUTIC COMPOSITIONS FOR SKIN DISORDERS AND WOUND REPAIR | UNIVERSITY OF MIAMI (US) | 2023-11-02 | — | — | WO | claimed |
| US-20220110979-A1 | FIBROBLAST REGENERATIVE CELLS | FIGENE, LLC | 2022-04-14 | — | — | US | claimed |
| EP-3908297-A1 | FIBROBLAST REGENERATIVE CELLS | Figene, LLC (US) | 2021-11-17 | — | — | EP | claimed |
| CN-113198019-A | Medicine formula for treating initial stage of new coronavirus pneumonia infection | 叶绍朋 | 2021-08-03 | — | — | CN | claimed |
| EP-3279663-B1 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | BRIGHAM & WOMENS HOSPITAL INC (US) | 2021-07-28 | — | — | EP | claimed |
| CN-107085113-B | Use of gelsolin for diagnosis and treatment of inflammatory diseases | 布赖汉姆妇女医院有限公司 | 2020-07-17 | — | — | CN | claimed |
| WO-2020146874-A1 | FIBROBLAST REGENERATIVE CELLS | FIGENE, LLC (US) | 2020-07-16 | — | — | WO | claimed |
| EP-3279663-A1 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | The Brigham and Women's Hospital, Inc. (US) | 2018-02-07 | — | — | EP | claimed |
| US-20170281724-A9 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-10-05 | — | — | US | claimed |
| EP-2001496-B1 | USE OF GELSOLIN TO DIAGNOSE AND TREAT INFLAMMATORY DISEASES | BRIGHAM & WOMENS HOSPITAL INC (US) | 2017-05-31 | — | — | EP | claimed |
| WO-1999022716-A1 | TOPICAL COMPOSITIONS FOR NSAI DRUG DELIVERY | NEXMED HOLDINGS, INC. (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1998043630-A1 | MEANS OF ASCERTAINING AN INDIVIDUAL'S RISK PROFILE FOR ATHEROSCLEROTIC DISEASE | BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 1998-10-08 | — | — | WO | claimed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| EP-0221753-B1 | TRANSDERMAL TREATMENT FOR PAIN AND INFLAMMATION WITH 2-AMINO-3-AROYLBENZENEACETIC ACIDS, SALTS AND ESTERS | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1992-01-08 | — | — | EP | claimed |
| EP-0225005-B1 | ANTI-INFLAMMATORY ANALGESIC ADHESIVE PREPARATION | NITTO DENKO CORPORATION (JP) | 1990-03-14 | — | — | EP | claimed |
| US-4740374-A | Anti-inflammatory analgesic adhesive preparation | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1988-04-26 | — | — | US | claimed |
| US-4683242-A | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-07-28 | — | — | US | claimed |
| EP-0225005-A1 | Anti-inflammatory analgesic adhesive preparation | NITTO DENKO CORPORATION (JP) | 1987-06-10 | — | — | EP | claimed |
| EP-0221753-A2 | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-05-13 | — | — | EP | claimed |
| US-4045576-A | ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-30 | — | — | US | claimed |