Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235368 | 0.77 | ALDH1A1 (0.47) | HRH3HRH2HRH1KDM4EMEN1 | |
| SCHEMBL30239652 | 0.76 | HRH3 (0.50) | HRH3HRH2HRH1SLC6A4KCNJ1 | |
| SCHEMBL7468442 | 0.75 | CYP2A6 (0.42) | HRH3KDM4EMEN1ALDH1A1GFER | |
| SCHEMBL12663039 | 0.74 | ALDH1A1 (0.55) | HRH3HRH1KDM4EMEN1ALDH1A1 | |
| SCHEMBL63804 | 0.74 | ALDH1A1 (0.52) | KDM4EMEN1ALDH1A1GFERKMT2A | |
| SCHEMBL5296696 | 0.73 | HRH3 (0.74) | HRH3HRH2HRH1 | |
| SCHEMBL2156764 | 0.73 | ALDH1A1 (0.55) | HRH3KDM4EMEN1ALDH1A1GFER | |
| SCHEMBL6555097 | 0.73 | ALDH1A1 (0.50) | HRH3KDM4EMEN1ALDH1A1GFER | |
| SCHEMBL7498982 | 0.72 | KCNJ1 (0.67) | HRH3HRH2HRH1CACNA1BCACNA1H | |
| Hydrochloric Acid SCHEMBL11222216 | 0.71 | ALDH1A1 (0.53) | HRH3KDM4EMEN1ALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | HRH3 210/4885HRH2 162/4885HRH1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.