Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4234624 | 0.87 | ALDH1A1 (0.45) | SLC6A2SLC6A4SLC6A3SSTR5ALDH1A1 | |
| SCHEMBL4225162 | 0.87 | CYP19A1 (0.39) | SLC6A2SLC6A4SSTR5HRH1HTR2B | |
| SCHEMBL4232088 | 0.86 | SSTR5 (0.44) | SSTR5HRH1HTR2BALDH1A1KCNH2 | |
| SCHEMBL4232885 | 0.86 | SSTR5 (0.46) | SSTR5HRH1ALDH1A1KCNH2DRD2 | |
| SCHEMBL4236623 | 0.86 | SSTR5 (0.41) | SLC6A2SLC6A4SLC6A3SSTR5ALDH1A1 | |
| SCHEMBL4232220 | 0.86 | SSTR5 (0.46) | SSTR5HRH1ALDH1A1KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL4232793 | 0.84 | PAX8 (0.39) | SSTR5MCHR1KCNH2DRD2DRD4 | |
| SCHEMBL4233908 | 0.83 | SSTR5 (0.44) | SSTR5HRH1HTR2BALDH1A1KCNH2 | |
| SCHEMBL4234997 | 0.83 | MAPT (0.36) | SLC6A2SLC6A4SLC6A3SSTR5ALDH1A1 | |
| SCHEMBL4954333 | 0.82 | SSTR5 (0.42) | SSTR5MCHR1HRH1HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |