Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.69 |
| ▸ | GRM6 | O15303 | 1/20 | 0.69 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.69 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.69 |
| ▸ | GSR | P00390 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.69 |
| ▸ | GRM5 | P41594 | 1/20 | 0.69 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.69 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.69 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.69 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.69 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.69 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.69 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.69 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.69 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.69 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.69 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL5178589 | 1.00 | GRM8 (0.69) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL4234244 | 1.00 | GRM8 (0.69) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Methionine SCHEMBL542055 | 0.94 | BHMT (0.61) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Racemethionine SCHEMBL542054 | 0.94 | BHMT (0.61) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamine SCHEMBL8082384 | 0.93 | ALOX15 (0.63) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamine SCHEMBL8082387 | 0.93 | ALOX15 (0.63) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL12276999 | 0.93 | GRM8 (0.60) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL2728602 | 0.92 | GRM8 (0.58) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL9393949 | 0.90 | SLC1A3 (0.56) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL9393952 | 0.90 | SLC1A3 (0.56) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072524-A2 | Anti-inflammatory peptides | Salpep Biotechnology, Inc. (CA) | 2009-06-24 | — | — | EP | claimed |
| US-20070054865-A1 | Anti-inflammatory peptides | AIM THERAPEUTICS INC. (CA) | 2007-03-08 | — | — | US | claimed |
| EP-1474439-A2 | DIPEPTIDES AND TRIPEPTIDES WITH ANTI-INFLAMMATORY ACTIVITY | Salpep Biotechnology Inc. (CA) | 2004-11-10 | — | — | EP | claimed |
| US-20030195141-A1 | Anti-inflammatory peptides | AIM THERAPEUTICS INC. (CA) | 2003-10-16 | — | — | US | claimed |
| WO-2003066670-A2 | DIPEPTIDES AND TRIPEPTIDES WITH ANTI-INFLAMMATORY ACTIVITY | SALPEP BIOTECHNOLOGY INC. (CA) | 2003-08-14 | — | — | WO | claimed |
| EP-2072524-A2 | Anti-inflammatory peptides | Salpep Biotechnology, Inc. (CA) | 2009-06-24 | — | — | EP | disclosed |