Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221310 | 0.84 | CHRM1 (0.37) | CHRM1AVPR1ACHRM2CHRM4CHRM5 | |
| SCHEMBL1554091 | 0.81 | CHRM1 (0.49) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL4049616 | 0.73 | SIGMAR1 (0.49) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL4051360 | 0.72 | SIGMAR1 (0.47) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL4231625 | 0.71 | CHRM1 (0.53) | CHRM1CHRM4CHRM5MCHR1 | |
| SCHEMBL4239298 | 0.69 | CHRM1 (0.64) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL4236228 | 0.68 | SIGMAR1 (0.50) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL4432414 | 0.67 | ASAH1 (0.39) | — | |
| SCHEMBL4430264 | 0.67 | ALDH1A1 (0.42) | CHRM5CHRM3ADRA1AADRA1BKCNH2 | |
| SCHEMBL5448117 | 0.66 | PPARA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106534-A1 | NOVEL HETEROCYCLIC CARBOXAMIDES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |