Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113790 | 0.83 | MTNR1A (0.51) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL30159029 | 0.78 | MTNR1A (0.50) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL5779450 | 0.78 | MTNR1A (0.60) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL8135642 | 0.78 | MTNR1A (0.56) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL7771626 | 0.78 | MTNR1A (0.60) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL8827650 | 0.78 | MTNR1A (0.56) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL8134945 | 0.78 | MTNR1A (0.56) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL9039466 | 0.77 | MTNR1A (0.55) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL2127227 | 0.76 | MTNR1A (0.62) | MTNR1ADAOP2RX7PARP1CYP2C19 | |
| SCHEMBL30462513 | 0.75 | MTNR1A (0.57) | MTNR1ADAOP2RX7PARP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20090170790-A1 | KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-07-02 | — | — | US | disclosed |
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20060211636-A1 | Macrolide Antibiotics | ALIHODZIC SULEJMAN | 2006-09-21 | — | — | US | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
| US-20040077557-A1 | Macrolide antibiotics | GLAXO GROUP LIMITED (GB) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | MTNR1A 1447/4885DAO 4429/4885P2RX7 3979/4885 |
| US-20060211636-A1 | Macrolide Antibiotics | IL1R1, MRPL12, RPS21 | MTNR1A 1447/4885DAO 4429/4885P2RX7 3979/4885 |
| US-20090170790-A1 | KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | MGAM, HEXA, MGAM2 | MTNR1A 1628/4885DAO 3674/4885P2RX7 3647/4885 |
| US-20040077557-A1 | Macrolide antibiotics | MALT1, MRPL21, IL1R1 | MTNR1A 1392/4885DAO 4211/4885P2RX7 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.