Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632750 | 1.00 | NQO1 (0.50) | NQO1TSHRTDP1HPGDLMNA | |
| SCHEMBL9617380 | 0.82 | HRH3 (0.50) | NQO1TSHRTDP1HPGDLMNA | |
| SCHEMBL297343 | 0.79 | OPRM1 (0.51) | TSHRTDP1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL7600493 | 0.78 | OPRM1 (0.50) | TSHRTDP1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL7600489 | 0.78 | OPRM1 (0.50) | TSHRTDP1ALDH1A1CA12CA1 | |
| SCHEMBL20436808 | 0.77 | NQO1 (0.64) | NQO1TSHRTDP1HPGDLMNA | |
| SCHEMBL17767220 | 0.75 | NQO1 (0.61) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL8285036 | 0.75 | NQO1 (0.61) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL20766152 | 0.75 | NQO1 (0.61) | NQO1TSHRTDP1ACACBPARP10 | |
| Hydrochloric Acid SCHEMBL14120656 | 0.73 | NQO1 (0.58) | NQO1TSHRTDP1ACACBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099195-A1 | Therapeutic Compounds 570 | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099195-A1 | Therapeutic Compounds 570 | OPRL1, OPRK1, OPRM1 | NQO1 212/4885TSHR 1066/4885TDP1 3486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.