SCHEMBL4240262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4240266	1.00	ENPP2 (0.42)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4237561	0.92	MAPK1 (0.46)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4237563	0.92	MAPK1 (0.46)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4240327	0.91	ENPP2 (0.43)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4240330	0.91	ENPP2 (0.43)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4238446	0.83	MAPK1 (0.44)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4238440	0.83	MAPK1 (0.44)	ENPP2HDAC1KDM4EOPRM1OPRD1
	SCHEMBL4237289	0.83	NPC1 (0.42)	ENPP2HDAC1KDM4ELMNAPOLB
	SCHEMBL4237282	0.83	NPC1 (0.42)	ENPP2HDAC1KDM4ELMNAPOLB
	SCHEMBL4242458	0.81	ENPP2 (0.41)	ENPP2HDAC1DRD4DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.