Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730282 | 0.80 | ALDH1A1 (0.38) | TDP1FFAR1CPT2EPHX1MEN1 | |
| SCHEMBL5795037 | 0.78 | ALDH1A1 (0.39) | TDP1FFAR1CPT2MEN1KMT2A | |
| SCHEMBL18125947 | 0.76 | KDM4E (0.48) | TDP1FFAR1CPT2SMN1; SMN2HSD17B10 | |
| SCHEMBL25357456 | 0.75 | SMN1; SMN2 (0.37) | TDP1EPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11269180 | 0.73 | ALDH1A1 (0.30) | SMN1; SMN2POLB | |
| SCHEMBL14392982 | 0.73 | TDP1 (0.42) | TDP1FFAR1CPT2EPHX1MEN1 | |
| SCHEMBL1979548 | 0.73 | SMN1; SMN2 (0.38) | TDP1FFAR1CPT2SMN1; SMN2HSD17B10 | |
| SCHEMBL6729276 | 0.73 | SMN1; SMN2 (0.38) | TDP1FFAR1CPT2EPHX1KDM4C | |
| SCHEMBL22854215 | 0.72 | TDP1 (0.40) | TDP1FFAR1CPT2EPHX1MEN1 | |
| SCHEMBL5620319 | 0.71 | ALDH1A1 (0.44) | EPHX1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558257-B1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | GRUENENTHAL GMBH (DE) | 2013-12-25 | — | — | EP | claimed |
| EP-1515702-B1 | ABUSE-PROTECTED ADMINISTRATION FORM | GRUENENTHAL GMBH (DE) | 2008-10-15 | — | — | EP | claimed |
| EP-1558221-B1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | GRUENENTHAL GMBH (DE) | 2007-06-06 | — | — | EP | claimed |
| EP-1765303-B2 | ORAL TABLET SAFEGUARDED AGAINST ABUSE | GRUENENTHAL GMBH (DE) | 2022-11-23 | — | — | EP | disclosed |
| US-8722086-B2 | Dosage form with impeded abuse | GRUENENTHAL GMBH (DE) | 2014-05-13 | — | — | US | disclosed |
| US-20090004267-A1 | Dosage Form with Impeded Abuse | GRUENENTHAL GMBH (DE) | 2009-01-01 | — | — | US | disclosed |
| EP-0595364-B1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-07-24 | — | — | EP | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |
| EP-0595364-A1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-05-04 | — | — | EP | disclosed |