Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915798 | 0.84 | PAOX (0.38) | ALDH1A1HSD17B10KDM4CSMN1; SMN2TDP1 | |
| SCHEMBL2214465 | 0.84 | LMNA (0.41) | ALDH1A1HSD17B10KDM4CCYP2D6CYP2C19 | |
| SCHEMBL6729276 | 0.83 | SMN1; SMN2 (0.38) | ALDH1A1HSD17B10KDM4CSMN1; SMN2CYP2D6 | |
| SCHEMBL4240347 | 0.80 | TDP1 (0.43) | HSD17B10KDM4CSMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL6730280 | 0.80 | KDM4C (0.37) | ALDH1A1HSD17B10KDM4CCYP2D6CYP2C19 | |
| SCHEMBL23175464 | 0.79 | MEN1 (0.34) | ALDH1A1HSD17B10SMN1; SMN2TDP1MEN1 | |
| SCHEMBL20269362 | 0.79 | KDM4C (0.40) | ALDH1A1HSD17B10KDM4CSMN1; SMN2CYP2D6 | |
| SCHEMBL1979548 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1HSD17B10SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL20269674 | 0.77 | SMN1; SMN2 (0.38) | HSD17B10KDM4CSMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL22849847 | 0.77 | TDP1 (0.44) | ALDH1A1TDP1MEN1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | EGIS GYOGYSZERGYAR (HU) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | CYP2F1, CYP3A4, CYP2S1 | ALDH1A1 81/4885HSD17B10 688/4885KDM4C 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.