⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938633 | 0.79 | ALDH1A1 (0.68) | — | |
| SCHEMBL10766089 | 0.79 | THRB (0.71) | — | |
| SCHEMBL10774278 | 0.78 | TSHR (0.41) | — | |
| SCHEMBL1469988 | 0.77 | ALDH1A1 (0.65) | — | |
| SCHEMBL11416400 | 0.77 | ALDH1A1 (0.65) | — | |
| SCHEMBL24056 | 0.77 | — | — | |
| SCHEMBL1470175 | 0.77 | ALDH1A1 (0.65) | — | |
| SCHEMBL1470280 | 0.77 | ALDH1A1 (0.65) | — | |
| SCHEMBL4446590 | 0.77 | — | — | |
| SCHEMBL1470310 | 0.77 | ALDH1A1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065447-A | MONOAZO DYES | SANDOZ LTD. (CH) | 1977-12-27 | — | — | US | claimed |
| US-20090093473-A1 | Spiro-benzimidazoles as inhibitors of gastric acid secretion | NYCOMED GMBH (DE) | 2009-04-09 | — | — | US | disclosed |
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |
| US-20080280855-A1 | Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles | NYCOMED GMBH (DE) | 2008-11-13 | — | — | US | disclosed |
| EP-0984969-B1 | FUSED DIHYDROPYRANS | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008074858-A1 | INTERMEDIATES AND PROCESS FOR THE PRODUCTION OF 5-SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2008-06-26 | — | — | WO | disclosed |
| EP-1934215-A1 | ISOTOPICALLY SUBSTITUTED IMIDAZOPYRIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | Nycomed GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008071766-A2 | SPIRO-INDENE SUBSTITUTED IMIDAZONAPHYTHYRIDINE AND PYRANOIMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF GASTRIC ACID SECRETION | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-1998042707-A1 | TETRAHYDROPYRIDO COMPOUNDS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0569759-B1 | Benzisothiazolazo dyes with a coupling component of the aniline series | BASF AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |
| US-5342928-A | Disperse dyes for dyeing or printing textile fibers or fabrics | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| EP-0569759-A1 | Benzisothiazol and benzothiphenazo dyes with a coupling component of the aniline series | BASF Aktiengesellschaft (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0499822-A1 | Bichromophore methine dyes | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-4505857-A | DISPERSE DYES FOR TEXTILE DYEING; COLORFASTNESS | SANDOZ LTD. (CH) | 1985-03-19 | — | — | US | disclosed |
| US-4148791-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1979-04-10 | — | — | US | disclosed |
| US-4065447-A | MONOAZO DYES | SANDOZ LTD. (CH) | 1977-12-27 | — | — | US | disclosed |