Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236785 | 0.87 | TLR8 (0.37) | TLR8TLR7UBE2TASIC3NPC1 | |
| SCHEMBL6967203 | 0.81 | NPC1 (0.53) | TLR8TLR7UBE2TASIC3NPC1 | |
| SCHEMBL6705401 | 0.79 | GAA (0.38) | TLR8TLR7UBE2TASIC3NPC1 | |
| SCHEMBL1451349 | 0.78 | HDAC6 (0.44) | UBE2TASIC3KDM4EGAAHSD17B10 | |
| SCHEMBL2835433 | 0.78 | UBE2T (0.58) | UBE2TASIC3NPC1RAB9AKDM4E | |
| SCHEMBL2662248 | 0.76 | UBE2T (0.59) | TLR8TLR7UBE2TASIC3NPC1 | |
| SCHEMBL2096363 | 0.74 | DRD2 (0.40) | TLR8TLR7NPC1RAB9AMAPK1 | |
| SCHEMBL19067624 | 0.73 | MAPT (0.46) | TLR8TLR7NPC1RAB9AKDM4E | |
| SCHEMBL24947150 | 0.72 | OGA (0.38) | TLR8TLR7UBE2TASIC3NPC1 | |
| SCHEMBL693161 | 0.72 | SMN1; SMN2 (0.47) | NPC1RAB9AKDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036428-A2 | 1,3,4-TRISUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |