Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.53 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233136 | 0.86 | TEAD3 (0.51) | LTA4HNPC1RAB9AHRH3TEAD3 | |
| SCHEMBL2088353 | 0.81 | KDM4E (0.75) | SMN1; SMN2NPC1RAB9AHRH3KDM4E | |
| SCHEMBL2741684 | 0.81 | LTA4H (0.59) | LTA4HHRH3ALDH1A1HRH1KCNH2 | |
| SCHEMBL22386773 | 0.81 | LTA4H (0.59) | LTA4HHRH3ALDH1A1HRH1KCNH2 | |
| SCHEMBL12128564 | 0.81 | LTA4H (0.56) | LTA4HCYP2D6HRH3ALDH1A1SLC6A2 | |
| SCHEMBL22440218 | 0.81 | LTA4H (0.77) | LTA4HSMN1; SMN2NPC1RAB9AHRH3 | |
| SCHEMBL12128487 | 0.80 | HRH3 (0.62) | LTA4HCYP2D6HRH3MAOBHRH1 | |
| SCHEMBL12128585 | 0.80 | HRH3 (0.62) | LTA4HCYP2D6HRH3MAOBHRH1 | |
| Hydrochloric Acid SCHEMBL4224584 | 0.80 | KDM4E (0.73) | SMN1; SMN2NPC1RAB9AHRH3KDM4E | |
| SCHEMBL2087691 | 0.80 | KDM4E (0.72) | LTA4HSMN1; SMN2NPC1RAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | LTA4H 1731/4885CYP2D6 1331/4885SMN1; SMN2 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.