Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.57 |
| ▸ | HRH2 | P25021 | 9/20 | 0.52 |
| ▸ | HRH1 | P35367 | 9/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237843 | 0.84 | HRH3 (0.72) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL4240622 | 0.81 | HRH2 (0.47) | HRH3HRH2HRH1 | |
| SCHEMBL4237104 | 0.81 | HRH3 (0.85) | HRH3HRH2HRH1SIGMAR1MEN1 | |
| SCHEMBL4237090 | 0.77 | HRH3 (0.46) | HRH3HRH2HRH1SIGMAR1MEN1 | |
| SCHEMBL5206619 | 0.73 | HRH3 (1.00) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL7745171 | 0.72 | MEN1 (0.51) | HRH3HRH2HRH1SIGMAR1MEN1 | |
| SCHEMBL7745176 | 0.72 | MEN1 (0.51) | HRH3HRH2HRH1SIGMAR1MEN1 | |
| SCHEMBL7745173 | 0.72 | MEN1 (0.51) | HRH3HRH2HRH1SIGMAR1MEN1 | |
| SCHEMBL1715421 | 0.71 | HRH3 (0.93) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL5208517 | 0.71 | HRH3 (1.00) | HRH3HRH2HRH1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | HRH3 210/4885HRH2 162/4885HRH1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.