Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | HRH2 | P25021 | 6/20 | 0.47 |
| ▸ | HRH1 | P35367 | 6/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745176 | 1.00 | MEN1 (0.51) | MEN1HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL7745171 | 1.00 | MEN1 (0.51) | MEN1HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL8718292 | 0.88 | HRH3 (0.49) | MEN1HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL5083235 | 0.86 | KMT2A (0.44) | KMT2A | |
| SCHEMBL5076788 | 0.85 | KDM4E (0.48) | MEN1KMT2A | |
| SCHEMBL7745181 | 0.84 | MEN1 (0.46) | MEN1SIGMAR1KMT2A | |
| SCHEMBL7745184 | 0.84 | MEN1 (0.46) | MEN1SIGMAR1KMT2A | |
| SCHEMBL7745178 | 0.84 | MEN1 (0.46) | MEN1SIGMAR1KMT2A | |
| SCHEMBL7412808 | 0.84 | HRH3 (0.46) | MEN1HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL9094149 | 0.83 | HRH3 (0.44) | MEN1HRH3HRH2HRH1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032178-A1 | USE OF 3,4-SUBSTITUTED PIPERIDINES | NOVO NORDISK A/S (DK) | 2001-05-10 | — | — | WO | claimed |
| WO-2001032178-A1 | USE OF 3,4-SUBSTITUTED PIPERIDINES | NOVO NORDISK A/S (DK) | 2001-05-10 | — | — | WO | disclosed |