Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063851 | 0.93 | ALDH1A1 (0.62) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4065469 | 0.85 | ALDH1A1 (0.43) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4063572 | 0.83 | ALDH1A1 (0.78) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4074550 | 0.83 | KDM4E (0.62) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4067228 | 0.79 | KDM4E (0.57) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4746294 | 0.77 | ALDH1A1 (0.43) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4749859 | 0.77 | ALDH1A1 (0.43) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4248613 | 0.76 | KDM4E (0.43) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4749923 | 0.76 | KDM4E (0.44) | HPGDHSD17B10KDM4EALDH1A1NPSR1 | |
| SCHEMBL4067394 | 0.74 | HSD17B10 (0.47) | HPGDHSD17B10KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706412-A4 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK CHEMICALS CO LTD (KR) | 2009-03-18 | — | — | EP | disclosed |
| EP-1706412-A1 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK Chemicals, Co., Ltd. (KR) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005063768-A1 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK CHEMICALS, CO., LTD. (KR) | 2005-07-14 | — | — | WO | disclosed |