Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749923 | 0.99 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4749360 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL4749965 | 0.90 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL4749356 | 0.88 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL4787866 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10OGA | |
| SCHEMBL4063851 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4747065 | 0.83 | LIPE (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4749859 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4787804 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL4746748 | 0.78 | L3MBTL1 (0.44) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |