SCHEMBL4241

SCHEMBL4241

CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.34
ESR2 Q92731 3/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.33
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
TSHR P16473 3/20 0.32
TAAR1 Q96RJ0 2/20 0.31
ALOX15 P16050 1/20 0.31
SLC6A2 P23975 1/20 0.31
AKT1 P31749 1/20 0.31
AKT2 P31751 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6391397 0.97 ESR1 (0.33) ESR1ESR2ALDH1A1CYP3A4MAPK1
SCHEMBL2492802 0.95 ESR1 (0.32) ESR1ESR2ALDH1A1CYP3A4MAPK1
SCHEMBL9815122 0.93 ESR1 (0.35) ESR1ESR2ALDH1A1CYP3A4MAPK1
SCHEMBL28398399 0.89
SCHEMBL16458730 0.85 MAPT (0.33) ALDH1A1TSHRLMNAALOX12ACHE
SCHEMBL14837511 0.82 TAAR1 (0.34) TAAR1
SCHEMBL12816750 0.81 TP53 (0.39) ALDH1A1MAPK1LMNA
SCHEMBL12815755 0.80 MEN1 (0.30) ALDH1A1
SCHEMBL9812985 0.80 NR1H2 (0.33) NR1H2NR1H3TSHR
Imidazole SCHEMBL7679091 0.80 ALDH1A1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16740 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071504-A Oxime-decorated glycosyl thioether, and preparation method and application thereof 四川大学华西医院 2026-05-22 CN claimed
CN-119504910-B Method for preparing plant-derived cholesterol through chemical catalysis 湖北葛店人福药用辅料有限责任公司 2026-05-15 CN claimed
CN-122010712-A Synthesis method of bevacizidine and intermediate thereof 扬州奥锐特药业有限公司 2026-05-12 CN claimed
CN-122010814-A (2S, 4R) -1-Fmoc-4- (O-allyloxycarbonyl methyl) -proline and synthesis method thereof 杭州澳赛诺医药技术有限公司 2026-05-12 CN claimed
CN-119569721-B Preparation method of PM-PBB3 and analogues thereof 烟台皓元生物医药科技有限公司 2026-02-27 CN claimed
EP-4688154-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - Portela & Ca., S.A. (PT) 2026-02-11 EP claimed
EP-4688155-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS Bial-Portela & CA, S.A. (PT) 2026-02-11 EP claimed
US-12497416-B2 Acylphosphine oxide compounds and preparation methods thereof ANHUI CHICHEM CORPORATION (CN) 2025-12-16 US claimed
US-20250270202-A1 SUBSTITUTED 4-AMINOISOINDOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2025-08-28 US claimed
CN-120136914-A Preparation and application technology of fluoride ion fluorescent probe DCF based on V-type biscoumarin 南京林业大学 2025-06-13 CN claimed
EP-0059094-B1 NOVEL CYCLOHEPTANES ORTHO PHARMACEUTICAL CORPORATION (US) 1985-07-31 EP claimed
US-4481279-A Dry-developing resist composition FUJITSU LIMITED (JP) 1984-11-06 US claimed
US-4464455-A Dry-developing negative resist composition FUJITSU LIMITED (JP) 1984-08-07 US claimed
US-4391975-A TREATING AN AZETIDINE DERIVATIVE WITH A FLUORINE COMPOUND TO EFFECT CYCLIZATION QUEEN'S UNIVERSITY AT KINGSTON (CA) 1983-07-05 US claimed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
US-4360467-A Process for preparing 8-oxabicyclo[3.2.1]-octane-1-acetic acids ORTHO PHARMACEUTICAL CORPORATION (US) 1982-11-23 US claimed
EP-0059094-A1 Novel cycloheptanes ORTHO PHARMACEUTICAL CORPORATION (US) 1982-09-01 EP claimed
US-4296035-A Total synthesis of the utero-evacuant substance d,l-zoapatanol ORTHO PHARMACEUTICAL CORPORATION (US) 1981-10-20 US claimed
US-4190457-A CONTACTING WITH ORGANOSILICON COMPOUND, DRYING, INCREASING PORE VOLUME PHILLIPS PETROLEUM CO. (US) 1980-02-26 US claimed