SCHEMBL9812985

SCHEMBL9812985

CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CCCC[Si](C)(C)Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
PCSK9 Q8NBP7 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4241 0.80 ESR1 (0.34) NR1H2NR1H3TSHR
SCHEMBL28069640 0.80 ESR1 (0.34) NR1H2NR1H3TSHR
SCHEMBL9815122 0.78 ESR1 (0.35) NR1H2NR1H3
SCHEMBL6391397 0.78 ESR1 (0.33) NR1H2NR1H3TSHR
SCHEMBL27840073 0.78 ESR1 (0.33) NR1H2NR1H3TSHR
Toluene SCHEMBL27521778 0.77 LMNA (0.44) NR1H3PCSK9TSHRELANE
SCHEMBL14837511 0.76 TAAR1 (0.34)
SCHEMBL2492802 0.76 ESR1 (0.32) NR1H2NR1H3
SCHEMBL1315203 0.74 TSHR (0.35) NR1H2NR1H3PCSK9TSHR
SCHEMBL4930368 0.72 TSHR (0.35) NR1H2NR1H3PCSK9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760904-A1 METHOD FOR PRODUCING A MOLDED FOAM ELEMENT Eurofoam GmbH (AT) 2014-08-06 EP disclosed
WO-2012135888-A1 METHOD FOR PRODUCING A MOLDED FOAM ELEMENT EUROFOAM GMBH (AT) 2012-10-11 WO disclosed
EP-0427773-A1 METHOD OF PREPARATION OF 2',3'-DIDEOXYNUCLEOSIDES THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1991-05-22 EP disclosed
WO-1990001492-A1 METHOD OF PREPARATION OF 2',3'-DIDEOXYNUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1990-02-22 WO disclosed