Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653414 | 0.86 | KCNH2 (0.55) | KCNH2MCHR1 | |
| SCHEMBL13653388 | 0.85 | KCNH2 (0.58) | KCNH2MCHR1 | |
| SCHEMBL4569934 | 0.84 | KCNH2 (0.45) | KCNH2MCHR1 | |
| SCHEMBL4565591 | 0.75 | KCNH2 (0.41) | KCNH2MCHR1IDO1 | |
| SCHEMBL4566462 | 0.74 | KCNH2 (1.00) | KCNH2MCHR1 | |
| SCHEMBL13653451 | 0.72 | KCNH2 (0.72) | KCNH2MCHR1 | |
| SCHEMBL15977222 | 0.71 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL26684007 | 0.70 | HTR1F (0.56) | KCNH2 | |
| SCHEMBL4237052 | 0.69 | MCHR1 (0.38) | KCNH2MCHR1 | |
| SCHEMBL4457815 | 0.68 | MCHR1 (0.50) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |