Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565591 | 0.72 | KCNH2 (0.41) | MCHR1KCNH2KDM5B | |
| SCHEMBL13622711 | 0.71 | MCHR1 (0.41) | MCHR1KCNH2KDM5B | |
| SCHEMBL4241013 | 0.69 | KCNH2 (0.58) | MCHR1KCNH2 | |
| SCHEMBL4374344 | 0.69 | MCHR1 (0.39) | MCHR1 | |
| SCHEMBL11559004 | 0.64 | ALDH1A1 (0.49) | — | |
| SCHEMBL15977222 | 0.62 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL13653389 | 0.62 | GSK3B (0.39) | MEN1KMT2APSDKDM5B | |
| SCHEMBL4078373 | 0.60 | OPRM1 (0.47) | MCHR1KCNH2 | |
| SCHEMBL18870144 | 0.59 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL12059313 | 0.59 | MCHR1 (0.68) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |