Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4241090 | 0.86 | NTSR1 (0.43) | NTSR1KDM4EMAPTNPSR1PDGFRB | |
| SCHEMBL4240982 | 0.86 | ROCK1 (0.34) | NTSR1KMT2A | |
| SCHEMBL4244642 | 0.85 | NTSR1 (0.43) | NTSR1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL4247339 | 0.82 | MALT1 (0.35) | KDM4EMAPTNPSR1KMT2A | |
| SCHEMBL4243183 | 0.79 | PIK3R2 (0.37) | KDM4EMEN1KMT2A | |
| SCHEMBL4242771 | 0.79 | MALT1 (0.34) | KDM4E | |
| SCHEMBL4244710 | 0.78 | NTSR1 (0.39) | NTSR1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL4241610 | 0.78 | ROCK1 (0.39) | NTSR1PDGFRB | |
| SCHEMBL4247324 | 0.77 | ADRB2 (0.42) | KDM4EMAPTNPSR1PDGFRB | |
| Hydrochloric Acid SCHEMBL4236201 | 0.77 | ADRB2 (0.41) | KDM4EMAPTNPSR1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638521-B2 | 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-12-29 | — | — | US | disclosed |