Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241320 | 1.00 | GPR84 (0.37) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL6427261 | 0.94 | CA12 (0.39) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL23829900 | 0.86 | CA12 (0.35) | MAPTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL11583564 | 0.86 | CA12 (0.35) | MAPTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL4771375 | 0.83 | NOD1 (0.44) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL4771369 | 0.83 | NOD1 (0.44) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL15047641 | 0.81 | NOD1 (0.46) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL28655988 | 0.81 | NOD1 (0.46) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL8859855 | 0.80 | GPR84 (0.40) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL29001879 | 0.80 | NOD1 (0.39) | GPR84FFAR1PPARDMAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085695-A1 | TREATMENT OR PREVENTION OF SKIN INJURY DUE TO EXPOSURE TO ULTRAVIOLET LIGHT | HORWITZ LAWRENCE D (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090169497-A1 | Treatment and Prevention of Skin Injury Due to Exposure to Ultraviolet Light | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2009-07-02 | — | — | US | disclosed |
| EP-1203583-B1 | REMEDIES FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1203583-B1 | REMEDIES FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| CN-1184965-C | therapeutic agent for osteoarthritis | SANTEN PHARMACEUTICAL CO LTD (JP) | 2005-01-19 | — | — | CN | disclosed |
| EP-1203583-A4 | REMEDIES FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6576668-B1 | Mercaptoacylcysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-6576668-B1 | Mercaptoacylcysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| CN-1356898-A | Remedies for arthrosis deformans | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-07-03 | — | — | CN | disclosed |
| EP-1203583-A1 | REMEDIES FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
| EP-1203583-A1 | REMEDIES FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
| JP-2001064168-A | THERAPEUTIC AGENT FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUT CO LTD | 2001-03-13 | — | — | JP | disclosed |
| WO-2000078305-A1 | REMEDIES FOR ARTHROSIS DEFORMANS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-12-28 | — | — | WO | disclosed |
| US-4621151-A | Optical resolution of DL-cysteine | Nohira, Hiroyuki (JP) | 1986-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169497-A1 | Treatment and Prevention of Skin Injury Due to Exposure to Ultraviolet Light | MGMT, S100A6, S100A9 | GPR84 3230/4885FFAR1 2227/4885PPARD 1436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.