SCHEMBL4241874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4245958	0.92	TLR7 (0.46)	NPC1TLR7SIRT3TLR8HPGD
	SCHEMBL14572367	0.91	TLR7 (0.44)	NPC1TLR7SIRT3POLBTP53
	Trifluoroacetic Acid SCHEMBL4245762	0.88	TLR7 (0.42)	NPC1TLR7SIRT3POLBTP53
	SCHEMBL4239881	0.84	TLR7 (0.46)	TLR7TLR8
	SCHEMBL4242126	0.84	TLR7 (0.46)	NPC1TLR7FKBP1ASMN1; SMN2POLB
	SCHEMBL4240504	0.83	FKBP1A (0.46)	NPC1TLR7FKBP1ASMN1; SMN2POLB
	SCHEMBL4244181	0.82	TLR7 (0.48)	TLR7TLR8KDM4EALDH1A1HPGD
	SCHEMBL14572660	0.80	TLR7 (0.53)	TLR7FKBP1ASMN1; SMN2POLBTLR8
	SCHEMBL4245516	0.79	TLR7 (0.43)	TLR7TLR8
	SCHEMBL4237213	0.78	TLR7 (0.48)	TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.