Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056293 | 0.80 | CLK1 (0.43) | MEN1KMT2AHTTALDH1A1MAOA | |
| SCHEMBL4066605 | 0.73 | CLK1 (0.60) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL10192294 | 0.73 | CLK1 (0.43) | MEN1KMT2AHTTALDH1A1MAOA | |
| SCHEMBL9339385 | 0.71 | KMT2A (0.41) | MEN1KMT2AHTTALDH1A1MAOA | |
| SCHEMBL4794811 | 0.70 | CLK1 (0.53) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL15004754 | 0.66 | MEN1 (0.47) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL11584329 | 0.66 | LMNA (0.56) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL17735499 | 0.65 | NPC1 (0.62) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL4066328 | 0.65 | HTT (0.56) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL23886831 | 0.65 | ESR1 (0.34) | NPSR1KDM4EESRRAESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |