Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075635 | 0.78 | MAPT (0.48) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL1670080 | 0.75 | MAOA (0.39) | KMT2AMEN1ALDH1A1HTTMAPK1 | |
| SCHEMBL12377649 | 0.75 | HTT (0.39) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL1668123 | 0.74 | MAPT (0.44) | KMT2AMEN1ALDH1A1POLBTSHR | |
| SCHEMBL12387042 | 0.74 | MEN1 (0.38) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL8871817 | 0.73 | KMT2A (0.51) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL4242839 | 0.71 | MEN1 (0.40) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL23886817 | 0.71 | KDM4E (0.40) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL30176370 | 0.71 | KDM4E (0.40) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL10192294 | 0.69 | CLK1 (0.43) | KMT2AMEN1ALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371239-A | Pyrrole nitrile or nitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |