Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27670166 | 0.90 | MAOB (0.54) | MAOBPARP14GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27670147 | 0.89 | MAOB (0.52) | MAOBPARP14GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27689183 | 0.89 | MAOB (0.54) | MAOBPARP14GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27670393 | 0.89 | MAOB (0.54) | MAOBPARP14PARP10GRIN2BGRIN2D | |
| SCHEMBL4243512 | 0.88 | GAA (0.55) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4250186 | 0.88 | MAOB (0.51) | MAOBPARP10GAA | |
| SCHEMBL27670194 | 0.87 | PARP14 (0.47) | MAOBPARP14GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27670143 | 0.87 | MAOB (0.52) | MAOBPARP14GRIN2BGRIN2DGRIN3B | |
| SCHEMBL19994530 | 0.87 | MAOB (0.56) | MAOBGRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27689205 | 0.86 | PARP10 (0.58) | MAOBPARP14PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | claimed |
| CN-1989119-A | New benzoyl urea derivatives | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | claimed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | claimed |
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
| CN-1989119-A | New benzoyl urea derivatives | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | MAOB 399/4885PARP14 3613/4885PARP10 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.