Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242914 | 0.87 | MAOB (0.54) | MAOBFAAHGRIN2BGRIN2DGRIN3B | |
| SCHEMBL28098494 | 0.86 | MAOB (0.57) | MAOBFAAHGRIN2BGRIN2DGRIN3B | |
| SCHEMBL8670678 | 0.86 | MAOA (0.55) | MAOBGRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL19994655 | 0.85 | FAAH (0.45) | MAOBFAAHGRIN2BALDH1A1GRIN2D | |
| SCHEMBL1581379 | 0.85 | FAAH (0.60) | MAOBFAAHMAPT | |
| SCHEMBL15954401 | 0.85 | MAOB (0.47) | MAOBFAAHGRIN2BGRIN2DGRIN3B | |
| SCHEMBL19994566 | 0.85 | MAOB (0.56) | MAOBFAAH | |
| SCHEMBL19026472 | 0.85 | FAAH (0.45) | MAOBFAAHGRIN2BGRIN2DGRIN3B | |
| SCHEMBL5169485 | 0.84 | FAAH (0.63) | FAAHKDM4ELMNAMAPT | |
| SCHEMBL19994570 | 0.84 | MAOB (0.59) | MAOBFAAHGRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426634-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | University of Ljubljana (SI) | 2019-01-16 | — | — | EP | disclosed |
| WO-2018055096-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF LJUBLJANA (SI) | 2018-03-29 | — | — | WO | disclosed |