SCHEMBL4242990

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4242987	1.00	ALDH1A1 (0.39)	ALDH1A1TSHRMEN1KMT2AMRGPRX4
	SCHEMBL4244304	0.91	TSHR (0.44)	ALDH1A1TSHRMEN1KMT2AGABRP
	SCHEMBL4244296	0.91	TSHR (0.44)	ALDH1A1TSHRMEN1KMT2AGABRP
	SCHEMBL13743178	0.90	MEN1 (0.38)	ALDH1A1TSHRMEN1KMT2AGABRP
	SCHEMBL4236903	0.81	FDFT1 (0.50)	ALDH1A1TDP1
	SCHEMBL6002288	0.81	MEN1 (0.43)	ALDH1A1TSHRMEN1KMT2AGABRP
	SCHEMBL4236896	0.81	FDFT1 (0.50)	ALDH1A1TDP1
	SCHEMBL4240157	0.73	PPARG (0.46)	ALDH1A1KMT2ANPC1RAB9AKDM4E
	SCHEMBL13743321	0.73	FDFT1 (0.51)	ALDH1A1
	SCHEMBL4119074	0.71	NPC1 (0.47)	ALDH1A1MEN1KMT2AMRGPRX4RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.