Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | RORB | Q92753 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244304 | 1.00 | TSHR (0.44) | TSHRMEN1KMT2ARORCRORB | |
| SCHEMBL4242987 | 0.91 | ALDH1A1 (0.39) | TSHRMEN1KMT2ARORCRORB | |
| SCHEMBL4242990 | 0.91 | ALDH1A1 (0.39) | TSHRMEN1KMT2ARORCRORB | |
| SCHEMBL6002288 | 0.90 | MEN1 (0.43) | TSHRMEN1KMT2ARORCRORB | |
| SCHEMBL4236903 | 0.76 | FDFT1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL4236896 | 0.76 | FDFT1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL10713056 | 0.72 | RORC (0.56) | TSHRMEN1KMT2ARORCRORB | |
| SCHEMBL4236612 | 0.71 | PPARG (0.51) | RORCRORBALDH1A1GABRPGABRD | |
| SCHEMBL6953363 | 0.71 | GABRP (0.52) | RORBALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL8785645 | 0.69 | KCNMA1 (0.63) | TSHRMEN1KMT2ARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215743-A1 | Tricyclic benzazepine derivatives and their use | BAYER HEALTHCARE AG (DE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215743-A1 | Tricyclic benzazepine derivatives and their use | CACNA1I, HDAC3, AADAC | TSHR 2095/4885MEN1 3901/4885KMT2A 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.