SCHEMBL993045

SCHEMBL993045

O=C(c1ccccc1)C1C=CC(F)(F)C=C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.45
MAPT P10636 2/20 0.40
HTT P42858 2/20 0.40
ALOX15 P16050 1/20 0.40
HBB P68871 1/20 0.40
EPHX1 P07099 3/20 0.39
CES2 O00748 2/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 2/20 0.36
HSD17B10 Q99714 2/20 0.36
GAA P10253 1/20 0.36
PTPN1 P18031 1/20 0.36
GSK3B P49841 1/20 0.36
MCL1 Q07820 1/20 0.36
CYP2C19 P33261 2/20 0.35
CYP3A4 P08684 1/20 0.35
PARP1 P09874 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4959086 0.87 CES1 (0.39) CES1MAPTHTTALOX15HBB
SCHEMBL7420069 0.85 HTT (0.40) CES1MAPTHTTALOX15HBB
SCHEMBL7423415 0.85 CES1 (0.38) CES1MAPTHTTALOX15HBB
SCHEMBL7430909 0.85 CES1 (0.38) CES1MAPTHTTALOX15HBB
SCHEMBL136598 0.82 MAPT (0.41) CES1MAPTHTTALOX15HBB
SCHEMBL8574301 0.81 TSHR (0.39) CES1MAPTHTTALOX15HBB
SCHEMBL8488412 0.81 CES1 (0.35) CES1MAPTHTTALOX15HBB
SCHEMBL363122 0.81 MAPT (0.40) CES1MAPTHTTALOX15HBB
SCHEMBL156512 0.81 MAPT (0.40) CES1MAPTHTTALOX15HBB
SCHEMBL3270605 0.81 MAPT (0.40) CES1MAPTHTTALOX15HBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118280634-A Graphene conductive slurry dispersing agent and preparation method thereof 鸡西瀚宇石墨烯科技有限公司 2024-07-02 CN claimed
CN-118136322-A Corrosion-resistant power cable and preparation method thereof 广东佰佳电线电缆实业有限公司 2024-06-04 CN claimed
CN-118126282-A Amphoteric block copolymer and preparation method and application thereof 河北工业大学 2024-06-04 CN claimed
CN-117843996-A Spherical polyether-ether-ketone micropowder and preparation method and application thereof 上海森桓新材料科技有限公司 2024-04-09 CN claimed
CN-117645717-A Thermosetting polyaryletherketone, composite material, preparation method and application of thermosetting polyaryletherketone 中国科学院大连化学物理研究所 2024-03-05 CN claimed
CN-117626665-A Carbon fiber material with biological activity, preparation method thereof, composite material and application 东华大学 2024-03-01 CN claimed
CN-117587558-A Corrosion-resistant yarn and preparation method thereof 界首市双力线业有限公司 2024-02-23 CN claimed
CN-113952846-B Heat-resistant zwitterionic polyether-ether-ketone loose nanofiltration membrane and preparation method and application thereof 天津工业大学 2024-01-26 CN claimed
CN-114752056-B Device and method for repeatedly and stably producing polyaryletherketone with narrow molecular weight distribution 双驱智能科技(宁波)有限公司 2024-01-26 CN claimed
CN-117143495-A Epoxy resin anticorrosive paint and preparation method thereof 吉林大学 2023-12-01 CN claimed
CN-111342096-A Pyridine cross-linked anion exchange membrane for fuel cell and preparation method thereof 长春工业大学 2020-06-26 CN claimed
CN-108117640-B Preparation method of chlorosulfonated polyether-ether-ketone composite material film 宜宾天原集团股份有限公司 2020-06-09 CN claimed
CN-108102502-B Preparation method of water-soluble polyether-ether-ketone coating 宜宾天原集团股份有限公司 2020-06-05 CN claimed
CN-109616689-B Cross-linked anion exchange membrane and preparation method thereof 长春工业大学 2020-05-15 CN claimed
CN-110967421-A Method for detecting related substances of flunarizine hydrochloride preparation 正大青春宝药业有限公司 2020-04-07 CN claimed
CN-110790919-A Soluble polyaryletherketone terpolymer and synthesis method thereof 南京清研高分子新材料有限公司 2020-02-14 CN claimed
CN-108155325-A Preparation method of polymer diaphragm based on lithium/sodium ion battery 深圳市计量质量检测研究院 2018-06-12 CN claimed
CN-106431858-A Synthetic method of flunarizine medicine intermediate 4,4-difluorobenzophenone 厦门莱恩斯特信息科技有限公司 2017-02-22 CN claimed
CN-103515634-B A kind of synthesis of vanadium redox battery amberplex and preparation method NANTONG HANRUI NEW MATERIAL TECHNOLOGY Co.,Ltd. (CN) 2016-02-03 CN claimed
WO-1998000385-A1 PROCESS FOR PRODUCING BENZOPHENONE COMPOUNDS ALLIEDSIGNAL INC. (US) 1998-01-08 WO claimed