SCHEMBL528381

SCHEMBL528381

NC1(N)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
TSHR P16473 2/20 0.40
POLB P06746 2/20 0.40
HSD17B10 Q99714 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP2C19 P33261 2/20 0.40
HTT P42858 2/20 0.40
ALOX15 P16050 1/20 0.40
HBB P68871 1/20 0.40
CYP3A4 P08684 1/20 0.40
PARP1 P09874 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
EPHX1 P07099 2/20 0.39
CES1 P23141 3/20 0.38
CES2 O00748 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL11243926 0.86 CES2 (0.41) HSD17B10L3MBTL1CYP2C19TDP1CES1
SCHEMBL6510160 0.85 MAPT (0.38) MAPTTSHRPOLBHSD17B10L3MBTL1
Hydrochloric Acid SCHEMBL8844129 0.84 HTT (0.39) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL5677227 0.83 CES2 (0.41) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL136598 0.82 MAPT (0.41) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL10578743 0.81 CES1 (0.37) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL10586210 0.81 CES2 (0.38) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL10581258 0.81 MAPT (0.39) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL10583727 0.81 TSHR (0.39) MAPTTSHRPOLBHSD17B10L3MBTL1
SCHEMBL993045 0.81 CES1 (0.45) MAPTTSHRPOLBHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806685-B Polyimide film and preparation method thereof 苏州市奥贝新材料科技有限公司 2023-04-18 CN claimed
CN-115806685-A Polyimide film and preparation method thereof 苏州市奥贝新材料科技有限公司 2023-03-17 CN claimed
CN-114276542-A Preparation method of flame-retardant polyimide 无锡创彩光学材料有限公司 2022-04-05 CN claimed
CN-114231172-A UV-resistant hydrophobic membrane material and preparation method and application thereof 苏州东杏表面技术有限公司 2022-03-25 CN claimed
CN-109897378-B Polyimide composite film containing functionalized carbon quantum dots and preparation method thereof 浙江福斯特新材料研究院有限公司 2021-08-10 CN claimed
CN-112708273-A Resin composition 广东彤泰新材料科技有限公司 2021-04-27 CN claimed
CN-111848955-A Boron nitride-nitrile rubber graft modified polyimide insulating material and preparation method thereof 王康 2020-10-30 CN claimed
CN-109545578-A The derivative one-dimensional nitrogen-doped nanometer carbon electrode material of acylamide polymer and preparation method 中南民族大学 2019-03-29 CN claimed
CN-103756383-B Cured film Antiblock coating composition and corresponding two-sided cured film 张家港康得新光电材料有限公司 2016-09-07 CN claimed
EP-2726552-A2 POLYIMIDE-COATED FILLERS E. I. Du Pont de Nemours and Company (US) 2014-05-07 EP claimed
CN-103756383-A Anti-adhesion coating composition used for hard coating and corresponding double-sided hard coating ZHANGJIAGANG KANGDE XIN PHOTOELECTRIC MATERIAL CO LTD 2014-04-30 CN claimed
WO-2013003397-A2 POLYIMIDE-COATED FILLERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-01-03 WO claimed
WO-2012015205-A1 REFLECTION SHEET FOR BACKLIGHT UNIT SKC HAAS DISPLAY FILM COMPANY (KR) 2012-02-02 WO claimed
WO-2006059825-A1 METHOD OF SURFACE MODIFICATION OF POLYIMIDE FILM, MANUFACTURING METHOD OF FLEXIBLE COPPER CLAP LAMINATE AND ITS PRODUCT THEREBY KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2006-06-08 WO claimed
EP-0277038-B1 Multi-color transfer image forming method KONISHIROKU PHOTO IND (JP) 1994-11-23 EP claimed
US-5364731-A Images on multilayer elements formed by development, transferring to receivers KONICA CORPORATION (JP) 1994-11-15 US claimed
EP-0277038-A2 Multi-color transfer image forming method KONICA CORPORATION (JP) 1988-08-03 EP claimed
US-12612539-B2 Radiation curable (meth)acrylic adhesive composition HENKEL AG & CO. KGAA (DE) 2026-04-28 US disclosed
EP-0277038-A2 Multi-color transfer image forming method KONICA CORPORATION (JP) 1988-08-03 EP disclosed
US-4734486-A Polyamide comprising fluorinated xylyene moieties ICI AMERICAS INC. (US) 1988-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612539-B2 Radiation curable (meth)acrylic adhesive composition XRCC5, CAD, MMAB MAPT 656/4885TSHR 3099/4885POLB 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.