Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.60 |
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CDC25C | P30307 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 2/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758305 | 0.83 | KIF11 (0.69) | KIF11CDC25ACDC25CKDM4EALDH1A1 | |
| SCHEMBL29250372 | 0.83 | KIF11 (0.69) | KIF11CDC25ACDC25CKDM4EALDH1A1 | |
| SCHEMBL33523872 | 0.83 | KIF11 (0.69) | KIF11CDC25ACDC25CKDM4EALDH1A1 | |
| SCHEMBL29368226 | 0.83 | KIF11 (0.75) | KIF11CDC25ACDC25CKDM4EALDH1A1 | |
| SCHEMBL5466693 | 0.83 | KIF11 (0.75) | KIF11CDC25ACDC25CKDM4EALDH1A1 | |
| SCHEMBL30914261 | 0.83 | KIF11 (0.75) | KIF11CDC25ACDC25CKDM4EALDH1A1 | |
| SCHEMBL3472897 | 0.82 | KIF11 (0.53) | KIF11CDC25ACDC25CPARP1KDM4E | |
| SCHEMBL23132405 | 0.81 | CDK4 (0.50) | KIF11CDC25ACDC25CPARP1KDM4E | |
| SCHEMBL23530348 | 0.79 | KIF11 (0.59) | KIF11CDC25ACDC25CPARP1KDM4E | |
| SCHEMBL11995709 | 0.78 | PARP1 (0.55) | PARP1KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | KIF11 4361/4885CDC25A 39/4885CDC25C 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.