Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18280130 | 0.98 | GBA1 (0.57) | GBA1SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL21408968 | 0.91 | SLC6A4 (0.50) | GBA1SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29889730 | 0.91 | SLC6A4 (0.50) | GBA1SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL28254019 | 0.87 | KMT2A (0.50) | SLC6A2SLC6A4SLC6A3MGLLDRD2 | |
| SCHEMBL12807560 | 0.84 | SLC6A2 (0.51) | GBA1SLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL1532823 | 0.83 | SLC6A2 (0.50) | GBA1SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL26703855 | 0.81 | MGLL (0.47) | MGLLCCR3 | |
| SCHEMBL28128625 | 0.81 | SLC6A4 (0.63) | GBA1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL6927185 | 0.81 | MGLL (0.50) | GBA1SLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL18280151 | 0.80 | SLC6A4 (0.62) | GBA1SLC6A2SLC6A4SLC6A3HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | GBA1 3315/4885SLC6A2 2087/4885SLC6A4 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.