Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4243822

CCCCCCCCCCCCC1CC(=O)N(C2CC(C)(C)NC(C)(C)C2)C1=O.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP19A1 P11511 6/20 0.33
LMNA P02545 2/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HLCS P50747 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11125192 0.99 ALDH1A1 (0.35) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL39157 0.99 ALDH1A1 (0.35) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL14822502 0.99 ALDH1A1 (0.35) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL3225241 0.99 ALDH1A1 (0.35) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL11125187 0.99 ALDH1A1 (0.35) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL3269617 0.99 ALDH1A1 (0.35) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL13779814 0.95 MAPK1 (0.38) ALDH1A1MAPK1CYP19A1LMNAMEN1
SCHEMBL28833723 0.93 LMNA (0.33) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL6050499 0.92 MAPK1 (0.32) ALDH1A1MAPK1L3MBTL1CYP19A1LMNA
SCHEMBL13588314 0.88 MAPK1 (0.38) ALDH1A1MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101516448-B Cosmetic preparation based on molecularly imprinted polymers BASF AG 2014-07-16 CN disclosed
CN-101516448-A Cosmetic preparation based on molecularly imprinted polymers BASF AG (DE) 2009-08-26 CN disclosed
EP-2066406-A2 COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS BASF SE (DE) 2009-06-10 EP disclosed
EP-1968642-A2 KERATIN-BINDING EFFECTOR MOLECULES AND METHOD FOR THE PRODUCTION THEREOF BY COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS BASF SE (DE) 2008-09-17 EP disclosed
EP-1957111-A2 METHOD FOR THE PRODUCTION OF A KERATIN-BINDING EFFECTOR MOLECULE BASF SE (DE) 2008-08-20 EP disclosed
EP-1957034-A2 CHIMERIC KERATIN-BINDING EFFECTOR PROTEINS BASF SE (DE) 2008-08-20 EP disclosed
WO-2008034764-A2 COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS BASF SE (DE) 2008-03-27 WO disclosed
WO-2007147445-A2 KERATIN-BINDING EFFECTOR MOLECULES, AND METHOD FOR THE PRODUCTION THEREOF BASF SE (DE) 2007-12-27 WO disclosed
WO-2007060116-A2 KERATIN-BINDING EFFECTOR MOLECULES AND METHOD FOR THE PRODUCTION THEREOF BY COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES THAT SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS BASF SE (DE) 2007-05-31 WO disclosed
WO-2007060117-A2 CHIMERIC KERATIN-BINDING EFFECTOR PROTEINS BASF SE (DE) 2007-05-31 WO disclosed