Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178621 | 1.00 | CNR1 (0.34) | CNR1BACE1ADRB3RGS12APOBEC3A | |
| SCHEMBL4243870 | 1.00 | CNR1 (0.34) | CNR1BACE1ADRB3RGS12APOBEC3A | |
| SCHEMBL4239581 | 0.81 | KDM4E (0.36) | CNR1ADRB3ADRB2CYP1A2CYP3A4 | |
| SCHEMBL4239577 | 0.81 | KDM4E (0.36) | CNR1ADRB3ADRB2CYP1A2CYP3A4 | |
| SCHEMBL4245083 | 0.77 | MAOB (0.37) | CNR1BACE1RGS12APOBEC3AAPOBEC3G | |
| SCHEMBL4245080 | 0.77 | MAOB (0.37) | CNR1BACE1RGS12APOBEC3AAPOBEC3G | |
| SCHEMBL4245055 | 0.77 | FFAR1 (0.33) | RGS12APOBEC3AAPOBEC3GCA1CYP1A2 | |
| SCHEMBL4245059 | 0.77 | FFAR1 (0.33) | RGS12APOBEC3AAPOBEC3GCA1CYP1A2 | |
| SCHEMBL4542365 | 0.77 | LMNA (0.45) | ADRB3ADRB2CYP1A2CYP2D6 | |
| SCHEMBL4542370 | 0.77 | LMNA (0.45) | ADRB3ADRB2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005354-A1 | New Amino Derivatives and Their Use as Pharmaceuticals | PFIZER, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20050288270-A1 | New aminopyridine derivatives and their use as pharmaceuticals | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288270-A1 | New aminopyridine derivatives and their use as pharmaceuticals | DRD2, DRD1, DRD3 | CNR1 448/4885BACE1 3432/4885ADRB3 14/4885 |
| US-20090005354-A1 | New Amino Derivatives and Their Use as Pharmaceuticals | DRD2, DRD1, DRD3 | CNR1 485/4885BACE1 2801/4885ADRB3 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.