Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 13/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.56 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27840101 | 0.85 | IMPDH2 (0.64) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL19954811 | 0.79 | IMPDH2 (0.54) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL9262012 | 0.79 | IMPDH2 (0.65) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL16370951 | 0.76 | IMPDH2 (0.66) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL30215898 | 0.76 | P2RX3 (0.70) | — | |
| SCHEMBL1493794 | 0.76 | P2RX3 (0.70) | — | |
| SCHEMBL18587464 | 0.74 | IMPDH2 (0.55) | IMPDH2IMPDH1 | |
| SCHEMBL8075634 | 0.73 | IMPDH2 (0.70) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL15786427 | 0.73 | IMPDH2 (0.57) | IMPDH2IMPDH1 | |
| SCHEMBL16388514 | 0.73 | IMPDH2 (0.61) | IMPDH2IMPDH1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |