Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928394 | 1.00 | SSTR1 (0.63) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL6430387 | 1.00 | SSTR1 (0.63) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL27472186 | 0.99 | SSTR1 (0.62) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL6723717 | 0.99 | SSTR1 (0.62) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hexane SCHEMBL27589497 | 0.93 | SSTR1 (0.56) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL3012885 | 0.90 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL13244865 | 0.90 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL27542605 | 0.90 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL1723213 | 0.90 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL3019998 | 0.89 | SSTR1 (0.52) | SSTR1HTR2AADRB1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638546-B1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2009-12-29 | — | — | US | claimed |
| US-7638546-B1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2009-12-29 | — | — | US | disclosed |
| US-7566734-B2 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070299073-A1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2007-12-27 | — | — | US | disclosed |
| US-7238695-B2 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2007-07-03 | — | — | US | disclosed |
| US-6852725-B1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S. A. S. (FR) | 2005-02-08 | — | — | US | disclosed |
| EP-1086086-B1 | IMIDAZOLYL DERIVATIVES AND THEIR USE AS SOMATOSTATIN RECEPTOR LIGANDS | CONSEILS DE RECH SET D APPLIC (FR) | 2004-10-13 | — | — | EP | disclosed |
| US-20040176379-A1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2004-09-09 | — | — | US | disclosed |
| US-20040038970-A1 | Beta-carboline compounds | SOCIETE DE CONSEILS DE RECHERCHES ETD' APPLICATION SCIENTIFIQUES, S.A.S. A PARIS, FRANCE CORP. | 2004-02-26 | — | — | US | disclosed |
| EP-1086086-A1 | IMIDAZOLYL DERIVATIVES AND THEIR USE AS SOMATOSTATIN RECEPTOR LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064401-A2 | IMIDAZOLYL DERIVATIVES AND THEIR USE AS SOMATOSTATIN RECEPTOR LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299073-A1 | Imidazolyl derivatives | SSTR5, SSTR3, SSTR2 | SSTR1 4/4885HTR2A 245/4885ADRB1 115/4885 |
| US-20040038970-A1 | Beta-carboline compounds | SCN1B, SCN2B, CACNA1B | SSTR1 45/4885HTR2A 311/4885ADRB1 10/4885 |
| US-20040176379-A1 | Imidazolyl derivatives | SSTR5, SSTR3, SSTR2 | SSTR1 4/4885HTR2A 258/4885ADRB1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.