Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | AKT1 | P31749 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13244865 | 1.00 | SSTR1 (0.53) | SSTR1GPR84AKT1ROCK2PIM1 | |
| Hydrochloric Acid SCHEMBL3019998 | 0.99 | SSTR1 (0.52) | SSTR1GPR84AKT1ROCK2PIM1 | |
| SCHEMBL4244351 | 0.90 | SSTR1 (0.63) | SSTR1GPR84AKT1MAPTTDP1 | |
| SCHEMBL1928394 | 0.90 | SSTR1 (0.63) | SSTR1GPR84AKT1MAPTTDP1 | |
| SCHEMBL6430387 | 0.90 | SSTR1 (0.63) | SSTR1GPR84AKT1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL27472186 | 0.89 | SSTR1 (0.62) | SSTR1GPR84AKT1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL6723717 | 0.89 | SSTR1 (0.62) | SSTR1GPR84AKT1MAPTTDP1 | |
| SCHEMBL1926748 | 0.88 | HTR2A (0.56) | GPR84HTR2AHTR1AHTR2CSLC6A4 | |
| SCHEMBL1926750 | 0.88 | HTR2A (0.56) | GPR84HTR2AHTR1AHTR2CSLC6A4 | |
| SCHEMBL1926751 | 0.88 | HTR2A (0.56) | GPR84HTR2AHTR1AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184799-A1 | OXADIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184799-A1 | OXADIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | GPR119, SSTR3, SSTR2 | SSTR1 8/4885GPR84 200/4885AKT1 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.