Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.67 |
| ▸ | HTR2A | P28223 | 6/20 | 0.67 |
| ▸ | HTR1A | P08908 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 9/20 | 0.66 |
| ▸ | DRD4 | P21917 | 3/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MLNR | O43193 | 1/20 | 0.60 |
| ▸ | HTR3B | O95264 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403746 | 0.84 | DRD2 (0.66) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL3811683 | 0.84 | DRD2 (0.67) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL1114150 | 0.83 | DRD2 (0.64) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL1114311 | 0.82 | DRD2 (0.62) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL14494817 | 0.81 | DRD2 (0.66) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL28485682 | 0.81 | DRD2 (0.72) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL14494809 | 0.81 | DRD2 (0.66) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL251911 | 0.81 | DRD2 (1.00) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL14494808 | 0.81 | DRD2 (0.74) | DRD2HTR2AHTR1ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL28484110 | 0.81 | DRD2 (0.71) | DRD2HTR2AHTR1ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145590-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | disclosed |